We are oral health researchers improving health through patient-centered research and evidence implementation.
Caries is a global epidemic, but Europe suffers the highest burden. Latvia exemplifies this crisis: 93% of adolescents show visible tooth damage.
A population of 1.9 million enables rapid national-scale implementation. Evidence-based interventions can be implemented and evaluated at population scale, then adapted for international contexts.
Children's oral health reveals a nation's future. Caries today predicts diabetes tomorrow and cardiovascular disease in twenty years. This progression is preventable at the oral health stage, the moment of maximum impact and minimum cost. Countries prioritizing children's dental care gain immediate returns: children miss fewer school days and learn more effectively, while parents avoid the 3.5 workdays annually lost to managing children's dental emergencies. Long-term savings follow through lower chronic disease burden and healthier populations. But most importantly, because there is no health without oral health.
See by yourself below. Do you see a pattern? Countries with lower caries prevalence consistently show higher GDP, better educational outcomes, and lower chronic disease burden. Oral health predicts prosperity. We work to close this gap equipping clinicians with evidence, providing policymakers with cost-effectiveness data, and deploying technology to reduce the implementation gap.
Maldupa, I., Sopule, A., Uribe, S. E., Brinkmane, A., & Senakola, E. (2021). Caries Prevalence and Severity for 12-Year-Children in Latvia. International Dental Journal, 71(3), 206-215. https://doi.org/10.1111/idj.12627
Oral Health Research
Clinical and epidemiological studies with patient-centred outcomes
AI in Dentistry
Integrating AI into clinical and public health decision making
Data Analysis
Interpreting complex oral health data
Open Science
Transparent practices that increase research impact, reach, and reproducibility
Teaching
Clinical Research, Evidence-Based Practice, Cariology, Public Health, AI in Oral Health, Data Analysis
2008 Potential of Information Technology in Dental Education
Consensus document from the European Association of Dental Education guiding IT integration in dental curricula via e-learning, simulations, and assessments. Led by Nikos Mattheos, with Dr Uribe among contributors. Highlights faculty support needs, open access to quality-reviewed materials, content protection, and Web 2.0's role in global equity via initiatives.
2014 Latvian National Guideline for Fluoride Use
The Fluoride Use Guidelines for Latvia establish national standards for caries prevention. Profs. Ilze Maldupa and Sergio Uribe co-authored this 2014 document endorsed by the Latvian Dental Association. The guidelines provide evidence-based recommendations on water fluoridation, topical fluoride products, and school programs. This document directly influences clinical practice standards and public health policy in Latvia.
2023 National Oral Health Survey (2022-2023)
The SPKC Oral Health Epidemiologic 2022-2023 study surveyed 3,943 Latvian adolescents (ages 12 and 15) examining caries prevalence, severity, and risk factors using WHO protocols. Principal Investigators: Profs. Ilze Maldupa and Sergio Uribe. The study found only 14% of 12-year-olds were caries-free, with D3MFT indices (2.3 at age 12, 4.4 at age 15) exceeding European averages. Strong associations were identified between caries and inadequate fluoride toothpaste use, infrequent brushing, rural residence, and daily sugary drink consumption. This national baseline data informs Ministry of Health policy development, establishes evidence for fluoride standards and sugar reduction initiatives, and guides resource allocation for pediatric dental services across Latvia's regions.
2023 Child Dental Neglect Policy Compendium
The "Child Dental Neglect and Legal Protections" review compiles oral health profiles and policy briefs on child dental neglect legislation across 26 countries and Hong Kong SAR. Profs. Ilze Maldupa and Sergio Uribe were coauthors, providing documentation from Latvia and Chile. The analysis reveals 25/26 countries have general child neglect laws but only 2 specific to dental neglect; while specific laws foster supportive ecosystems to mitigate individual caries risk, they show limited impact on national untreated caries prevalence. It advocates integrating public health, human rights, and efficient criminal justice systems to enhance protections and access to oral healthcare globally.
2023 Artificial Intelligence for Oral and Dental Healthcare: Core Education Curriculum
Consensus curriculum from the IADR e-Oral Health Network and ITU/WHO Focus Group AI for Health defining essential learning outcomes for undergraduate and postgraduate dental AI education. Led by Falk Schwendicke, with Sergio Uribe among authors. Covers four domains—basic AI concepts and machine learning principles, use cases and software setups, evaluation metrics and health impacts, and ethical issues like explainability and governance—to introduce AI into dental curriculum worldwide.
2024 Dr Maldupa, representing Latvia, signed the WHO Bangkok Declaration.
In November 2024, Prof. Ilze Maldupa represented Latvia at the WHO Global Oral Health Meeting in Bangkok, signing the Bangkok Declaration—endorsed by over 100 member states—which asserts "no health without oral health" and promotes integrating essential dental care like fluoride and preventive treatments into primary health systems to reduce inequalities, aligning with Latvia's initiatives on sugar taxes and health education under the WHO Global Oral Health Action Plan 2023-2030.
2025 Sugar Taxation Policy Brief
The "Impact of Sugar Consumption on Physical and Mental Health" study provides economic evidence for reducing sugar intake in Latvia (60% adult, 25% child overweight/obesity rates). Co-investigator: Prof. Ilze Maldupa (RSU Institute of Public Health). The research links sugar consumption to caries, diabetes, cardiovascular disease, and healthcare costs. Evidence incorporated into Ministry of Health Action Plan 2025-2029, identifying sugar taxation as priority intervention. Status: Legislative consideration for 2026 budget.
2025 FDI World Dental Federation White Paper on Artificial Intelligence for Dentistry
The FDI World Dental Federation White Paper on Artificial Intelligence for Dentistry establishes global regulatory standards and ethical principles for AI in oral healthcare. Prof Uribe served on the working group that authored this document, leaded by Prof Schwendicke. The paper addresses data protection, algorithmic bias, clinical safety, and workforce implications. It provides evidence-based recommendations that shape how AI applications are developed, tested, and deployed in dental practice worldwide.
E. Uribe, S. (Project leader) & Maldupa, I. (Leading expert)
2/04/25 → 2/04/26
Sļepcova, O. (Project leader), Maldupa, I. (Supervisor) & E. Uribe, S. (Supervisor)
2/10/23 → 30/09/27
Project: PhD projects
Stāmere, U. (Project leader), Maldupa, I. (Supervisor) & E. Uribe, S. (Supervisor)
2/10/23 → 30/09/27
Project: PhD projects
Maldupa, I. (Project leader), E. Uribe, S. (Work package leader), Innes, N. (Leading expert), Marino, R. (Leading expert), Viduskalne, I. (Expert), Grišakova, J. (Expert), Stars, I. (Expert), Evans, D. (Expert), Stāmere, U. (Assistant (student)), Sļepcova, O. (Assistant (student)), Gostilo, D. (Assistant (student)), Protasa, N. (Assistant (student)) & Vagale, E. (Assistant (student))
1/01/23 → 31/12/25
Project: Fundamental and Applied Research Programme
Maldupa, I. (Project leader)
European Regional Development Fund, Latvia State Budget funding, Other funding source
1/03/20 → 28/02/23
Project: EU Structural Funds › ERDF
E. Uribe, S. (Project leader), Radziņš, O. (Expert) & Maldupa, I. (Leading expert)
26/07/21 → 25/07/22
Project: RSU grants
Ķīvīte-Urtāne, A. (Project leader), E. Uribe, S. (Expert), Maldupa, I. (Leading expert), et al.
1/07/20 → 31/03/21
Project: National Research Programme
We share our research datasets openly to support transparency, reproducibility, and new discoveries in oral health.
https://doi.org/10.5281/zenodo.15825108
https://doi.org/10.5281/zenodo.13208598
https://doi.org/10.5281/zenodo.13200856
https://doi.org/10.5281/zenodo.11507289
https://doi.org/10.5281/zenodo.10605383
https://doi.org/10.5281/zenodo.8074534
see Newsroom
Affiliations:
Associate Professor, Riga Stradins University, Latvia
Visiting Professor at LMU Munich, Germany
Lead Researcher, Institute of Stomatology, RSU & Baltic Biomaterials Centre of Excellence, Horizon 2020 857287
Education:
DDS, Universidad de Valparaiso, Chile.
MSc, Specialist in Oral & Maxillofacial Radiology, Universidad de Valparaiso, Chile.
PhD in Biomedical Sciences, Universidad Austral de Chile, Valdivia, Chile
Accreditations:
Clinical medicine, Expert, Latvian Council of Science
Editorial Boards
Awards
2007 Research in Prevention Award, IADR
Research Profiles
Affiliations:
Assistant Professor, Riga Stradins University.
Specialist Paediatric Dentistry, Institute of Stomatology, RSU
Education:
DDS, Riga Stradins University, Latvia
BDS, Universidad de Chile, Chile
PhD in Dental Science, Riga Stradins University, Latvia
Post-Doc Riga Stradins University, Latvia
Specialist in Pediatric Dentistry, Riga Stradins University, Latvia
Accreditations:
Clinical medicine, Expert, Latvian Council of Science
Editorial Boards
Awards
Research Profiles
Olga Sļepcova - 0000-0002-8723-5464
Una Stāmere - 0000-0002-7210-1463
Rafael Garbim (USP)
Artificial Intelligence for Oral Health Care: Applications and Future Prospects
Schwendicke, F., Chaudari, P. K., Dhingra, K., Uribe, S. E. & Hamdan, M.
This richly illustrated book offers a deeper understanding of the foundational concepts of AI, its practical applications in oral health, and the possibilities that lie ahead, with compelling, evidence-based insights into how AI is changing dentistry.
Covers a vast array of special topics e.g. basic concept, reporting guidelines, ethical and regulatory aspects
Offers a comprehensive review of rapidly expanding field of artificial intelligence (AI)
Provides readers with an up to date, evidence-based contemporary understanding of the subject
Scientific Writing and Publication Strategies for Oral Health Professionals
Rodrigo Mariño, Sergio E. Uribe, Ebingen Villavicencio-Caparó
This is the first-known book on research writing and scientific publication strategies specifically aimed at oral health professionals.
Offers an up-to-date practical guide for oral health & other health professionals on current/emerging publishing trends
Offers actionable tips using real-world examples of oral health research publication, simplifying the publishing process
Equips researchers with knowledge to identify and avoid predatory publishing, ensuring the credibility of their work
Bernuzobi.lv Project
EpiDentLatvia Project
Course: Introductory Clinical Research
Course: Short Introduction to Evidence Based Dentistry (3 weeks)
Course: Research Methodologies for Evidence-Based Dental Practice Course (2 semesters)
PODCAST: The Dental Research Lab
BLOG: Dental Research